Compile Data Set for Download or QSAR
maximum 50k data
Found 100 Enz. Inhib. hit(s) with all data for entry = 407
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2054(2,8-disubstituted dipyridodiazepinone 37 | 2-Chlor...)
Affinity DataIC50:  10nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2058(2,8-disubstituted dipyridodiazepinone 41 | 2-Chlor...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2058(2,8-disubstituted dipyridodiazepinone 41 | 2-Chlor...)
Affinity DataIC50:  20nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2054(2,8-disubstituted dipyridodiazepinone 37 | 2-Chlor...)
Affinity DataIC50:  20nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2057(2,8-disubstituted dipyridodiazepinone 40 | 2-Chlor...)
Affinity DataIC50:  30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2050(2,8-disubstituted dipyridodiazepinone 33 | 4-({2-e...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2050(2,8-disubstituted dipyridodiazepinone 33 | 4-({2-e...)
Affinity DataIC50:  30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y787L]/[600-1155,Y787L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2054(2,8-disubstituted dipyridodiazepinone 37 | 2-Chlor...)
Affinity DataIC50:  30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2048(2,8-disubstituted dipyridodiazepinone 31 | 2-Chlor...)
Affinity DataIC50:  40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2048(2,8-disubstituted dipyridodiazepinone 31 | 2-Chlor...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2036(2,8-disubstituted dipyridodiazepinone 18 | 2-Chlor...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase, V106AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2058(2,8-disubstituted dipyridodiazepinone 41 | 2-Chlor...)
Affinity DataIC50:  50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2022(2,8-Disubstituted Dipyridodiazepinone 36 | 2,8-Sub...)
Affinity DataIC50:  50nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2057(2,8-disubstituted dipyridodiazepinone 40 | 2-Chlor...)
Affinity DataIC50:  60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2057(2,8-disubstituted dipyridodiazepinone 40 | 2-Chlor...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2054(2,8-disubstituted dipyridodiazepinone 37 | 2-Chlor...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase P236LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2056(13-[(benzenesulfonyl)methyl]-5-chloro-2-ethyl-9-me...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2056(13-[(benzenesulfonyl)methyl]-5-chloro-2-ethyl-9-me...)
Affinity DataIC50:  60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2028(13-{[(3-aminophenyl)amino]methyl}-5-chloro-2-ethyl...)
Affinity DataIC50:  60nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2025(2,8-disubstituted dipyridodiazepinone 4 | 2-Chloro...)
Affinity DataIC50:  60nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2055(13-[(benzenesulfinyl)methyl]-5-chloro-2-ethyl-9-me...)
Affinity DataIC50:  70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2060(2,8-disubstituted dipyridodiazepinone 43 | 2-Chlor...)
Affinity DataIC50:  70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2048(2,8-disubstituted dipyridodiazepinone 31 | 2-Chlor...)
Affinity DataIC50:  70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2059(2,8-disubstituted dipyridodiazepinone 42 | 2-Chlor...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2059(2,8-disubstituted dipyridodiazepinone 42 | 2-Chlor...)
Affinity DataIC50:  70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2024(2,8-disubstituted dipyridodiazepinone 2 | 5-chloro...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2024(2,8-disubstituted dipyridodiazepinone 2 | 5-chloro...)
Affinity DataIC50:  80nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2021(2,8-Disubstituted Dipyridodiazepinone 37 | 2,8-Sub...)
Affinity DataIC50:  80nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2059(2,8-disubstituted dipyridodiazepinone 42 | 2-Chlor...)
Affinity DataIC50:  90nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2056(13-[(benzenesulfonyl)methyl]-5-chloro-2-ethyl-9-me...)
Affinity DataIC50:  100nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2028(13-{[(3-aminophenyl)amino]methyl}-5-chloro-2-ethyl...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2029(2,8-disubstituted dipyridodiazepinone 9 | 2-Chloro...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2028(13-{[(3-aminophenyl)amino]methyl}-5-chloro-2-ethyl...)
Affinity DataIC50:  100nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2052(2,8-disubstituted dipyridodiazepinone 35 | 2-Chlor...)
Affinity DataIC50:  100nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2029(2,8-disubstituted dipyridodiazepinone 9 | 2-Chloro...)
Affinity DataIC50:  100nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2038(13-(3-aminophenoxymethyl)-5-chloro-2-ethyl-9-methy...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2045(2,8-disubstituted dipyridodiazepinone 28 | 2-ethyl...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2025(2,8-disubstituted dipyridodiazepinone 4 | 2-Chloro...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2025(2,8-disubstituted dipyridodiazepinone 4 | 2-Chloro...)
Affinity DataIC50:  110nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2053(2,8-disubstituted dipyridodiazepinone 36 | 2-Chlor...)
Affinity DataIC50:  120nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2021(2,8-Disubstituted Dipyridodiazepinone 37 | 2,8-Sub...)
Affinity DataIC50:  120nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2060(2,8-disubstituted dipyridodiazepinone 43 | 2-Chlor...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2021(2,8-Disubstituted Dipyridodiazepinone 37 | 2,8-Sub...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y787L]/[600-1155,Y787L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2060(2,8-disubstituted dipyridodiazepinone 43 | 2-Chlor...)
Affinity DataIC50:  120nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y787L]/[600-1155,Y787L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2059(2,8-disubstituted dipyridodiazepinone 42 | 2-Chlor...)
Affinity DataIC50:  130nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2030(2,8-disubstituted dipyridodiazepinone 10 | 2-Chlor...)
Affinity DataIC50:  130nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2055(13-[(benzenesulfinyl)methyl]-5-chloro-2-ethyl-9-me...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2044(2,8-disubstituted dipyridodiazepinone 27 | 2-ethyl...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2055(13-[(benzenesulfinyl)methyl]-5-chloro-2-ethyl-9-me...)
Affinity DataIC50:  140nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2022(2,8-Disubstituted Dipyridodiazepinone 36 | 2,8-Sub...)
Affinity DataIC50:  150nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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