Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50048450
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14775BDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataKi:  0.400nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14775BDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214362BDBM50214362(CHEMBL102635)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataKi:  4.5nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214422BDBM50214422(CHEMBL101479)
Affinity DataIC50: 7nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214749BDBM50214749(CHEMBL102741)
Affinity DataIC50: 8nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214748BDBM50214748(CHEMBL103007)
Affinity DataIC50: 12nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214362BDBM50214362(CHEMBL102635)
Affinity DataKi:  12nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215126BDBM50215126(CHEMBL414417)
Affinity DataIC50: 14nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214380BDBM50214380(CHEMBL323132)
Affinity DataIC50: 16nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215942BDBM50215942(CHEMBL301201)
Affinity DataIC50: 18nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215127BDBM50215127(CHEMBL102310)
Affinity DataIC50: 19nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215125BDBM50215125(CHEMBL102503)
Affinity DataIC50: 20nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214506BDBM50214506(CHEMBL323069)
Affinity DataIC50: 22nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215108BDBM50215108(CHEMBL102758)
Affinity DataIC50: 24nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214422BDBM50214422(CHEMBL101479)
Affinity DataKi:  30nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215128BDBM50215128(CHEMBL318586)
Affinity DataIC50: 30nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215125BDBM50215125(CHEMBL102503)
Affinity DataKi:  30nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215127BDBM50215127(CHEMBL102310)
Affinity DataKi:  38nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215123BDBM50215123(CHEMBL102876)
Affinity DataIC50: 38nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214790BDBM50214790(CHEMBL262269)
Affinity DataIC50: 46nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214506BDBM50214506(CHEMBL323069)
Affinity DataKi:  51nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214749BDBM50214749(CHEMBL102741)
Affinity DataKi:  60nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215057BDBM50215057(CHEMBL322837)
Affinity DataKi:  64nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214380BDBM50214380(CHEMBL323132)
Affinity DataKi:  67nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215126BDBM50215126(CHEMBL414417)
Affinity DataKi:  67nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214748BDBM50214748(CHEMBL103007)
Affinity DataKi:  71nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215057BDBM50215057(CHEMBL322837)
Affinity DataIC50: 80nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215128BDBM50215128(CHEMBL318586)
Affinity DataKi:  86nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215108BDBM50215108(CHEMBL102758)
Affinity DataKi:  86nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215937BDBM50215937(CHEMBL299332)
Affinity DataIC50: 100nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215123BDBM50215123(CHEMBL102876)
Affinity DataKi:  116nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215937BDBM50215937(CHEMBL299332)
Affinity DataKi:  120nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215942BDBM50215942(CHEMBL301201)
Affinity DataKi:  135nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214790BDBM50214790(CHEMBL262269)
Affinity DataKi:  135nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215124BDBM50215124(CHEMBL104780)
Affinity DataKi:  225nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214384BDBM50214384(CHEMBL101368)
Affinity DataIC50: 260nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 320nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215058BDBM50215058(CHEMBL321760)
Affinity DataKi:  393nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215058BDBM50215058(CHEMBL321760)
Affinity DataIC50: 420nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215124BDBM50215124(CHEMBL104780)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214384BDBM50214384(CHEMBL101368)
Affinity DataKi:  1.12E+3nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215121BDBM50215121(CHEMBL102020)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of phosphodiesterase type IV (PDE4) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215121BDBM50215121(CHEMBL102020)
Affinity DataKi:  3.18E+3nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed