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Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50034974
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  1.96nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  12.6nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataIC50:  89nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  479nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  479nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  690nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  917nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50:  920nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  2.11E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  2.11E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)
Affinity DataIC50:  3.47E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)
Affinity DataIC50:  3.47E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed