Reaction Details  Report a problem with these data
Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM225312
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/10/17
ΔG°:
-7.88±0.06 (kcal/mole)
Temperature:
298±0 (K)
ΔH° :
-7.25±0.67 (kJ/mole)
ΔS° :
0±0 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2-CyclinA D3R  D3R Publication Date 6/30/2015 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Human
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM225312
Synonyms:
CS4
Type:
Small Organic Molecule
Emp. Form.:
C14H12N3O3
Mol. Mass.:
270.2639
SMILES:
[O-]C(=O)c1ccc(cc1)C(=O)Nc1cc([nH]n1)C1CC1
Structure:
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