Reaction Details Report a problem with these data
Target
Bromodomain-containing protein 2 [91-163]
Ligand
BDBM543629
Substrate
n/a
Meas. Tech.
AlphaLisa Assay
IC50
490±n/a nM
Citation
 Upadhayaya, RS; Kethiri, R; Madan, S; Rajaiah, SK Fused pyrimidine compounds as BRD4 and JAK2 dual inhibitors and methods for use thereof US Patent  US11279703 Publication Date 3/22/2022 
Target
Name:
Bromodomain-containing protein 2 [91-163]
Synonyms:
Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1) | Bromodomain-containing protein 2 (BRD2)(BD1) | BRD2_HUMAN | BRD2 | KIAA9001 | RING3
Type:
n/a
Mol. Mass.:
8836.08
Organism:
Human
Description:
BD1 (91-163 aa) of P25440
Residue:
73
Sequence:
WKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIV
  
Inhibitor
Name:
BDBM543629
Synonyms:
US11279703, TABLE 6.218 | US11279703, TABLE 6.263
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: