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Target
Arginase-1
Ligand
BDBM50561039
Substrate
n/a
Meas. Tech.
Biological Activity of Examples 1 to 30
IC50
1140±n/a nM
Citation
 Mlynarski, SN; Grebe, T; Kawatkar, S; Finlay, MR; Simpson, I; Wang, J; Cook, S; Wu, D Arginase inhibitors and methods of use thereof US Patent  US11420984 Publication Date 8/23/2022 
Target
Name:
Arginase-1
Synonyms:
Liver-type arginase | Type I arginase | ARGI1_HUMAN | ARG1
Type:
PROTEIN
Mol. Mass.:
34737.53
Organism:
Human
Description:
ChEMBL_978893
Residue:
322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
  
Inhibitor
Name:
BDBM50561039
Synonyms:
CHEMBL4749355 | US11420984, Example 23
Type:
Small organic molecule
Emp. Form.:
C10H21BN2O4
Mol. Mass.:
244.10
SMILES:
CN[C@H]1CN[C@](CCCCB(O)O)(C1)C(O)=O |r|
Structure:
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