Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM349513
Substrate
n/a
Meas. Tech.
Competitive Radioligand Binding Assay
Ki
120±n/a nM
Citation
 Rishton, GM; Catalano, SM; Look, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent  US11691947 Publication Date 7/4/2023 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Sigma-1 receptor | Sigma1-receptor | Sterol isomerase-like protein | Sigma1R | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | SGMR1_CAVPO | SIGMAR1 | OPRS1
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Guinea pig
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM349513
Synonyms:
US10207991, Ex. Cpd. No. 28 | US10611728, Example Compound 28 | US11691947, Example 28
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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