Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM349513
Substrate
n/a
Meas. Tech.
Competitive Radioligand Binding Assay
Ki
11.0±n/a nM
Citation
 Rishton, GM; Catalano, SM; Look, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent  US11691947 Publication Date 7/4/2023 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
Sigma intracellular receptor 2 | Sigma2 receptor | Transmembrane protein 97 | Sigma-2 receptor | SGMR2_RAT | Tmem97 | S2r
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rat
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM349513
Synonyms:
US10207991, Ex. Cpd. No. 28 | US10611728, Example Compound 28 | US11691947, Example 28
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: