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Target
Estrogen receptor [282-595]
Ligand
BDBM20607
Substrate
n/a
Meas. Tech.
ERα TR-FRET Test
IC50
578±n/a nM
Citation
 Yang, X; Zhu, C; Zhang, C; Talley, JJ; Chen, C; Bao, L; Min, X; Xu, L ESTROGEN RECEPTOR ANTAGONIST US Patent  US20240217988 Publication Date 7/4/2024 
Target
Name:
Estrogen receptor [282-595]
Synonyms:
Estrogen receptor (282-595)
Type:
Enzyme
Mol. Mass.:
35261.19
Organism:
Homo sapiens (Human)
Description:
P03372[282-595]
Residue:
314
Sequence:
SAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM20607
Synonyms:
(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine | CHEMBL83 | cid_2733526 | FOSTRIECIN SODIUM | 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine | Tamoxifen, 7 | Nolvadex | Tamoxifen | Tamoxifen (8) | NCGC00024928 | med.21724, Compound Tamoxifen | US20240217988, Example Tamoxifen
Type:
Small organic molecule
Emp. Form.:
C26H29NO
Mol. Mass.:
371.22
SMILES:
CC/C(=C(\c1ccccc1)/c2ccc(cc2)OCCN(C)C)/c3ccccc3
Structure:
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