Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM684673
Substrate
n/a
Meas. Tech.
Enzyme Assay
IC50
36800±n/a nM
Citation
 ROLFE, J; KHODABANDEH, M; ALPERSTEIN, Z; SABERALI, SA; MSLATI, H; GUZZO, P PROTEASE INHIBITORS AND METHODS OF MAKING SAME US Patent  US20240228460 Publication Date 7/11/2024 
Target
Name:
Procathepsin L
Synonyms:
Cathepsin L1 | Cathepsin L | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein | CTSL CTSL1 | CATL1_HUMAN | CTSL | CTSL1
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Human
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM684673
Synonyms:
US20240228460, Compound (102) | US20240228460, Compound (103)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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