Reaction Details Report a problem with these data
Target
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Ligand
BDBM701274
Substrate
n/a
Meas. Tech.
DXR Enzyme Activity Assay
IC50
3310±1020 nM
Citation
 Dowd, C; Odom John, A; Edwards, R; Heidel, KM; Wang, X; Chofor, R Antibiotics for veterinary staphylococcal infections US Patent  US12122799 Publication Date 10/22/2024 
Target
Name:
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms:
1-deoxyxylulose-5-phosphate reductoisomerase | 2-C-methyl-D-erythritol 4-phosphate synthase | DXP reductoisomerase
Type:
Protein
Mol. Mass.:
42232.93
Organism:
n/a
Description:
A0A7Z7QQH3
Residue:
376
Sequence:
MKNIAILGASGSIGQQAIDVIARHPESFNLISFTVGKNIEFAIEVIEKFKPEIVAVQDEADVERLKPYHSHIVSGRQGLIDVSTYEKNDLVLNALLGSVGLEPTMKAIEAGKNIALANKETLVVAGKLVMAHAKRYGVDILPVDSEHAAIFQCLNGEDMHQIKNVTITASGGSFRELTREQLEHVTVEDALNHPNWSMGNKITIDSATMMNKGFEVIEAKWLFDLEIDQIKTILHKESIIHSMVEFVDTSVMAQLGTPDMRMPIQYAFTYPERIEHRAPSLDLAQVSQLHFQEMDLDRYRCLKFAYDALRIGGSMPVVLNAVNEVAVAKFLNHEITFLEIEHMIEREMAAHEVIPDPSLEEILEIDHYYKTKPYEV
 
Inhibitor
Name:
BDBM701274
Synonyms:
US12122799, Compound ERJ-207
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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