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Target
Caspase-5
Ligand
BDBM160816
Substrate
n/a
Meas. Tech.
In Vitro Inhibitory Activity of Caspase
IC50
>3330±n/a nM
Citation
 Ahlfors, J; Mekouar, K Selective caspase inhibitors and uses thereof US Patent  US10167313 Publication Date 1/1/2019 
Target
Name:
Caspase-5
Synonyms:
Caspase-5 subunit p10 | Caspase-5 subunit p20 | ICE(rel)-III | TY protease | ICH-3 protease | Protease ICH-3 | CASP-5 | Caspase 5 | Protease TY | CASP5_HUMAN | CASP5 | ICH3
Type:
Enzyme
Mol. Mass.:
49760.80
Organism:
Human
Description:
P51878
Residue:
434
Sequence:
MAEDSGKKKRRKNFEAMFKGILQSGLDNFVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDSLRKNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
  
Inhibitor
Name:
BDBM160816
Synonyms:
US9045524, 85 | US10167313, Compound 85
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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