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Target
Bromodomain testis-specific protein [27-133]
Ligand
BDBM774946
Substrate
n/a
Meas. Tech.
Bromodomain Proximity Assay
IC50
14.0±n/a nM
Citation
 Matzuk, M; Yu, Z; Modukuri, R; Li, F; Young, D; Ucisik, MN; Faver, J; Tan, Z; Jin, Z; Anglin, J; Teng, M; Kim, C BROMODOMAIN AND EXTRA-TERMINAL (BET) SUBFAMILY BROMODOMAIN 1 (BD1) SELECTIVE INHIBITORS AND METHODS USING SAME US Patent  US20250304550 Publication Date 10/2/2025 
Target
Name:
Bromodomain testis-specific protein [27-133]
Synonyms:
BRDT_HUMAN | BRDT | BRDT-1 | Bromodomain testis-specific protein (BD1, aa 27-133)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12808.37
Organism:
Human
Description:
Q58F21[27-133]
Residue:
107
Sequence:
RLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM
  
Inhibitor
Name:
BDBM774946
Synonyms:
US20250304550, CDD-785 | US20250304550, Compound 12
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CNC(=O)C(CC1CCN(C(=O)Cc2ccc3[nH]c(=O)cc(C)c3c2)CC1)NC(=O)c1ccc(C(F)(F)F)cn1
Structure:
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