Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM349513
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
11.0±n/a nM
Citation
 Rishton, G; Catalano, SM; Look, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent  US9796672 Publication Date 10/24/2017 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
Meningioma-associated protein 30 | Sigma-2 receptor | Sigma2 receptor | Transmembrane protein 97 | SGMR2_HUMAN | TMEM97 | MAC30 | S2R
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Human
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM349513
Synonyms:
US10207991, Ex. Cpd. No. 28 | US10611728, Example Compound 28 | US11691947, Example 28
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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