Reaction Details Report a problem with these data
Target
A-kinase anchor protein 7 isoform gamma
Ligand
BDBM212594
Substrate
n/a
Meas. Tech.
Binding Assay
EC50
36400±n/a nM
Citation
 Tasken, K; Lygren, B; Ostensen, E; Klaveness, J Tertiary amines for use in the treatment of cardiac disorders US Patent  US9951033 Publication Date 4/24/2018 
Target
Name:
A-kinase anchor protein 7 isoform gamma
Synonyms:
A-kinase anchor protein 18 | AKA7G_MOUSE | AKAP-18 | AKAP-7 isoform gamma | Akap18 | Akap7 | PRKA7 isoform gamma | Protein kinase A-anchoring protein 7 isoform gamma
Type:
n/a
Mol. Mass.:
35486.56
Organism:
Mus musculus (Mouse)
Description:
Q7TN79
Residue:
314
Sequence:
MPFAAVDIQDDCGSPDVPQANPKRSKEEEEDRGDKNDHVKKRKKAKKDYQPNYFLSIPITNKKITTGIKVLQNSILQQDKRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLALPFQGIGTFQGQVGFVKLADGDHVSALLEIAETAKRTFREKGILAGESRTFKPHLTFMKLSKAPMLRKKGVRKIEPGLYEQFIDHRFGEELLYQIDLCSMLKKKQSNGYYHCESSIVIGEKDRREPEDAELVRLSKRLVENAVLKAVQQYLEETQNKKQPGEGNSTKAEEGDRNGDGSDNNRK
  
Inhibitor
Name:
BDBM212594
Synonyms:
US9556111, Table 1.2 | US9951033, Compound Table 1.6
Type:
Small organic molecule
Emp. Form.:
C19H16ClFN2O2S
Mol. Mass.:
390.859
SMILES:
OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2cccc(Cl)c2)n1
Structure:
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