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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM15581
Substrate
BDBM29135
Meas. Tech.
MAO Enzyme Inhibition Assay
pH
7.4000±n/a
Temperature
310.1500±n/a K
IC50
4.5±0.32 nM
Citation
 Chimenti, F; Fioravanti, R; Bolasco, A; Chimenti, P; Secci, D; Rossi, F; Yáñez, M; Orallo, F; Ortuso, F; Alcaro, S Chalcones: a valid scaffold for monoamine oxidases inhibitors. J Med Chem 52:2818-24 (2009) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
MAO-A | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) | Amine oxidase (flavin-containing) A | AOFA_HUMAN | MAOA
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Human
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM15581
Synonyms:
US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine | CHEMBL8706 | CLG | CLORGILINE | N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine | Clorgyline | US9603833, Clorgyline
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM29135
Synonyms:
CHEMBL11608 | cid_5610 | tyramine | p-Tyramine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: