Reaction Details Report a problem with these data
Target
Dual specificity protein kinase CLK1 [R432A]
Ligand
BDBM21079
Substrate
biotinylated affinity ligand
Meas. Tech.
Kinase Inhibitor Selectivity Profiling Assay
pH
7.4000±n/a
Temperature
296.1500±n/a K
Kd
8900±n/a nM
Citation
 PubChem, PC Kinase Inhibitor Selectivity Profiling Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Dual specificity protein kinase CLK1 [R432A]
Synonyms:
CDC-like kinase 1 | CLK1_HUMAN | CLK1 | CLK
Type:
Serine/threonine-protein kinase
Mol. Mass.:
57236.09
Organism:
Human
Description:
gi_632964
Residue:
484
Sequence:
MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIHHSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKSI
  
Inhibitor
Name:
BDBM21079
Synonyms:
1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluoranyl-5-methyl-phenyl)urea | CHEMBL223360 | 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea | cid_11485656 | 3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea | 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea | Aminoindazole, 3 | ABT-869 | US20250129067, Compound Linifanib
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
biotinylated affinity ligand
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA