Reaction Details Report a problem with these data
Target
Retinoic acid receptor beta [200-419]
Ligand
BDBM31882
Substrate
BDBM31883
Meas. Tech.
Retinoid Competition Binding Assay
pH
7.9±n/a
Temperature
277.15±n/a K
Kd
531±n/a nM
Citation
 Klaholz, BP; Mitschler, A; Moras, D Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J Mol Biol 302:155-70 (2000) [PubMed]  Article 
Target
Name:
Retinoic acid receptor beta [200-419]
Synonyms:
HAP | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic Acid Receptor, beta
Type:
Ligand-binding domain
Mol. Mass.:
24708.23
Organism:
Homo sapiens (Human)
Description:
P10826[200-419]
Residue:
220
Sequence:
PSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEG
  
Inhibitor
Name:
BDBM31882
Synonyms:
BMS184394-R | CHEMBL80992
Type:
Small organic molecule
Emp. Form.:
C26H28O3
Mol. Mass.:
388.4987
SMILES:
CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)c1ccc2cc(ccc2c1)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM31883
Synonyms:
9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC ACID | AT-RA | Atralin | CHEMBL38 | MLS000028588 | SMR000058245 | TRETINOIN | Vitamin A acid | [3H]RA | [3H]Retinoic acid | [3H]Vitamin A acid | [3H]tretinoin | all-trans retinoic acid | cid_444795
Type:
radiolabeled ligand
Emp. Form.:
C20H28O2
Mol. Mass.:
300.4351
SMILES:
C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O |c:4|
Structure:
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