Target
Retinoic acid receptor beta [200-419]
Ligand
BDBM31892
Substrate
BDBM31883
Meas. Tech.
Retinoid Competition Binding Assay
pH
7.9±n/a
Temperature
277.15±n/a K
Kd
0.2±n/a nM
Citation
 Klaholz, BPMitschler, AMoras, D Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J Mol Biol 302:155-70 (2000) [PubMed]  Article
Target
Name:
Retinoic acid receptor beta [200-419]
Synonyms:
Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | Retinoic Acid Receptor, beta
Type:
Ligand-binding domain
Mol. Mass.:
24708.23
Organism:
Homo sapiens (Human)
Description:
P10826[200-419]
Residue:
220
Sequence:
PSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEG
  
Inhibitor
Name:
BDBM31892
Synonyms:
9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin | alitretinoin
Type:
Small organic molecule
Emp. Form.:
C20H28O2
Mol. Mass.:
300.4351
SMILES:
C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O |c:4|
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM31883
Synonyms:
9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC ACID | AT-RA | Atralin | CHEMBL38 | MLS000028588 | SMR000058245 | TRETINOIN | Vitamin A acid | [3H]RA | [3H]Retinoic acid | [3H]Vitamin A acid | [3H]tretinoin | all-trans retinoic acid | cid_444795
Type:
radiolabeled ligand
Emp. Form.:
C20H28O2
Mol. Mass.:
300.4351
SMILES:
C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O |c:4|
Structure:
Search PDB for entries with ligand similarity: