Reaction Details Report a problem with these data
Target
Cathepsin Z
Ligand
BDBM36331
Substrate
BDBM36388
Meas. Tech.
Assay name: Protease Inhibition Assay
pH
5.5000±0.0000
Temperature
310.1500±0.0000 K
IC50
4.7e+3±n/a nM
Citation
 Kato, D; Boatright, KM; Berger, AB; Nazif, T; Blum, G; Ryan, C; Chehade, KA; Salvesen, GS; Bogyo, M Activity-based probes that target diverse cysteine protease families. Nat Chem Biol 1:33-8 (2005) [PubMed]  Article 
Target
Name:
Cathepsin Z
Synonyms:
CATZ_RAT | Ctsz | Ctsy
Type:
Protein
Mol. Mass.:
34197.61
Organism:
Rat
Description:
Q9R1T3
Residue:
306
Sequence:
MASSGSVQQLRLVLLMLLLAGAARASLYFRPGQTCYRPLHRDHLALLGRRTYPRPHEYLSPADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSALADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQECDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERMSNYTGGIYTEYQNQAIINHIISVAGWGVSNDGIEYWIVRNSWGEPWGERGWMRIVTSTYKGGTGSSYNLAIEEACTFGDPIV
  
Inhibitor
Name:
BDBM36331
Synonyms:
Ac-YFR-AMOK 10b
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM36388
Synonyms:
Octahydro-indolizine-1,6,7,8-tetraol, 13 | BDBM36404 | CID54445
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: