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Target
Pro-cathepsin H
Ligand
BDBM36331
Substrate
BDBM36388
Meas. Tech.
Assay name: Protease Inhibition Assay
pH
5.5000±0.0000
Temperature
310.1500±0.0000 K
IC50
1.2e+4±n/a nM
Citation
 Kato, D; Boatright, KM; Berger, AB; Nazif, T; Blum, G; Ryan, C; Chehade, KA; Salvesen, GS; Bogyo, M Activity-based probes that target diverse cysteine protease families. Nat Chem Biol 1:33-8 (2005) [PubMed]  Article 
Target
Name:
Pro-cathepsin H
Synonyms:
CATH_RAT | Ctsh | Cathepsin H
Type:
PROTEIN
Mol. Mass.:
37114.31
Organism:
Rat
Description:
P00786
Residue:
333
Sequence:
MWTALPLLCAGAWLLSAGATAELTVNAIEKFHFTSWMKQHQKTYSSREYSHRLQVFANNWRKIQAHNQRNHTFKMGLNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPSSMDWRKKGNVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMMTLAEQQLVDCAQNFNNHGCQGGLPSQAFEYILYNKGIMGEDSYPYIGKNGQCKFNPEKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFEVTEDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYGEQNGLLYWIVKNSWGSNWGNNGYFLIERGKNMCGLAACASYPIPQV
  
Inhibitor
Name:
BDBM36331
Synonyms:
Ac-YFR-AMOK 10b
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM36388
Synonyms:
Octahydro-indolizine-1,6,7,8-tetraol, 13 | BDBM36404 | CID54445
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: