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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43225
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
12310±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
Rac1 protein | RAC1_MOUSE | Rac1
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mouse
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43225
Synonyms:
MLS000736261 | 4-[4-(tert-butyl)phenyl]-2-[(4-methylphenyl)sulfanyl]-4-oxobutanoic acid | 4-(4-tert-butylphenyl)-2-[(4-methylphenyl)thio]-4-oxobutanoic acid | cid_4253856 | 4-(4-tert-butylphenyl)-2-(4-methylphenyl)sulfanyl-4-oxobutanoic acid | SMR000338511 | 4-(4-tert-butylphenyl)-2-(4-methylphenyl)sulfanyl-4-oxidanylidene-butanoic acid | 4-(4-tert-butylphenyl)-4-keto-2-(p-tolylthio)butyric acid
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: