Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43229
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
43190±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
Rac1 protein | RAC1_MOUSE | Rac1
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mouse
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43229
Synonyms:
[2-(cyclohexanecarbonylamino)-2-oxoethyl] 4-methylsulfonyl-3-nitrobenzoate | MLS000517530 | cid_2475979 | [2-(cyclohexylcarbonylamino)-2-oxidanylidene-ethyl] 4-methylsulfonyl-3-nitro-benzoate | SMR000343499 | 4-methylsulfonyl-3-nitrobenzoic acid [2-[[cyclohexyl(oxo)methyl]amino]-2-oxoethyl] ester | 4-mesyl-3-nitro-benzoic acid [2-(cyclohexanecarbonylamino)-2-keto-ethyl] ester
Type:
Small organic molecule
Emp. Form.:
C17H20N2O8S
Mol. Mass.:
412.09
SMILES:
CS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)OCC(=O)NC(=O)C1CCCCC1
Structure:
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