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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43286
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
46810±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
Rac1 protein | RAC1_MOUSE | Rac1
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mouse
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43286
Synonyms:
2-(4-fluorophenyl)sulfanylquinoline-4-carboxylic acid | cid_4137615 | UNM000011083701 | 2-[(4-fluorophenyl)thio]-4-quinolinecarboxylic acid | 2-[(4-fluorophenyl)thio]cinchoninic acid
Type:
Small organic molecule
Emp. Form.:
C16H10FNO2S
Mol. Mass.:
299.04
SMILES:
OC(=O)c1cc(Sc2ccc(F)cc2)nc2ccccc12
Structure:
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