Reaction Details Report a problem with these data
Target
Ras-related protein Rab-7a
Ligand
BDBM54703
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related protein Rab-7a
Synonyms:
RAB7A_CANLF | RAB7A | RAB7 | GTP-binding protein (rab7)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23519.50
Organism:
Dog
Description:
gi_164058
Residue:
207
Sequence:
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKTSAESCSC
  
Inhibitor
Name:
BDBM54703
Synonyms:
1-(4-methoxyphenyl)-3-phenyl-2-propyn-1-one | 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-one | cid_616715 | UNM-0000306061 | 1-(4-methoxyphenyl)-3-phenyl-prop-2-yn-1-one
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: