Reaction Details Report a problem with these data
Target
GTPase KRas [1-37]
Ligand
BDBM54685
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
Ki
5850±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Human
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54685
Synonyms:
7-bromanyl-3-[3-(oxidanylamino)-1H-indol-2-yl]indol-2-one | 7-bromo-3-[3-(hydroxyamino)-1H-indol-2-yl]-2-indolone | cid_11846148 | UNM-0000305775 | 7-bromo-3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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