Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM54692
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
Rac1 protein | RAC1_MOUSE | Rac1
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mouse
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM54692
Synonyms:
UNM-0000305782 | 2-amino-5-benzoyl-4-(3-bromo-4,5-dimethoxyphenyl)-1-(4-methoxyphenyl)sulfonylpyrrole-3-carbonitrile | 2-amino-5-benzoyl-4-(3-bromo-4,5-dimethoxyphenyl)-1-(4-methoxyphenyl)sulfonyl-3-pyrrolecarbonitrile | 2-azanyl-4-(3-bromanyl-4,5-dimethoxy-phenyl)-1-(4-methoxyphenyl)sulfonyl-5-(phenylcarbonyl)pyrrole-3-carbonitrile | cid_25220933 | 2-amino-5-benzoyl-4-(3-bromo-4,5-dimethoxy-phenyl)-1-(4-methoxyphenyl)sulfonyl-pyrrole-3-carbonitrile
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: