Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM54691
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
Ki
6050±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
Rac1 protein | RAC1_MOUSE | Rac1
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mouse
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM54691
Synonyms:
2-azanyl-5-(phenylcarbonyl)-4-(3,4,5-trimethoxyphenyl)-1-[2,4,6-tri(propan-2-yl)phenyl]sulfonyl-pyrrole-3-carbonitrile | 2-amino-5-benzoyl-4-(3,4,5-trimethoxyphenyl)-1-[2,4,6-tri(propan-2-yl)phenyl]sulfonylpyrrole-3-carbonitrile | UNM-0000305781 | cid_25220932 | 2-amino-5-benzoyl-4-(3,4,5-trimethoxyphenyl)-1-[2,4,6-tri(propan-2-yl)phenyl]sulfonyl-3-pyrrolecarbonitrile | 2-amino-5-benzoyl-1-(2,4,6-triisopropylphenyl)sulfonyl-4-(3,4,5-trimethoxyphenyl)pyrrole-3-carbonitrile
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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