Reaction Details Report a problem with these data
Target
Ras-related protein Rab-2A
Ligand
BDBM54685
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
EC50
65766±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2A_CANLF | RAB2A | RAB2 | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Dog
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM54685
Synonyms:
7-bromanyl-3-[3-(oxidanylamino)-1H-indol-2-yl]indol-2-one | 7-bromo-3-[3-(hydroxyamino)-1H-indol-2-yl]-2-indolone | cid_11846148 | UNM-0000305775 | 7-bromo-3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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