Reaction Details Report a problem with these data
Target
Ras-related protein Rab-2A
Ligand
BDBM54705
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2A_CANLF | RAB2A | RAB2 | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Dog
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM54705
Synonyms:
calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate | cid_16219353 | CHEMBL1297 | UNM-0000306101 | Fenoprofen | calcium;2-(3-phenoxyphenyl)propionic acid;hydrate
Type:
Small organic molecule
Emp. Form.:
C15H14O3
Mol. Mass.:
242.09
SMILES:
C[C@H](c1cccc(c1)Oc2ccccc2)C(=O)O
Structure:
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