Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM43273
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
>10000±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
DDIT3_MOUSE | Ddit3 | Chop | Chop10 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mouse
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM43273
Synonyms:
MLS000707180 | cid_1487004 | [5-(4-chlorophenyl)sulfonyl-1,2,3-thiadiazol-4-yl]-morpholin-4-yl-methanone | SMR000334562 | {5-[(4-chlorophenyl)sulfonyl]-1,2,3-thiadiazol-4-yl}(morpholino)methanone | [5-(4-chlorophenyl)sulfonylthiadiazol-4-yl]-morpholin-4-ylmethanone | [5-(4-chlorophenyl)sulfonyl-4-thiadiazolyl]-(4-morpholinyl)methanone | [5-(4-chlorophenyl)sulfonylthiadiazol-4-yl]-morpholino-methanone
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: