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Target
cAMP-dependent protein kinase type I-alpha regulatory subunit
Ligand
BDBM81287
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R1A (PKA-R1A) complex
EC50
2684±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R1A (PKA-R1A) complex PubChem Bioassay (2011)[AID] 
Target
Name:
cAMP-dependent protein kinase type I-alpha regulatory subunit
Synonyms:
cAMP-dependent protein kinase | KAP0_BOVIN | PRKAR1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42885.14
Organism:
Bovine
Description:
gi_115496662
Residue:
380
Sequence:
MASGTTASEEERSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQNLQKAGSRADSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
  
Inhibitor
Name:
BDBM81287
Synonyms:
SMR000450983 | cid_4132952 | 6-(6-aminopurin-9-yl)-2-ethoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol | MLS000766286 | 6-(6-aminopurin-9-yl)-2-ethoxy-2-oxidanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol | 6-(6-aminopurin-9-yl)-2-ethoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol | 6-adenin-9-yl-2-ethoxy-2-keto-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol
Type:
Small organic molecule
Emp. Form.:
C12H16N5O6P
Mol. Mass.:
357.08
SMILES:
CCOP1(=O)OCC2OC(C(O)C2O1)n1cnc2c(N)ncnc12
Structure:
Search PDB for entries with ligand similarity: