Reaction Details Report a problem with these data
Target
Tyrosine-protein kinase Lck
Ligand
BDBM81374
Substrate
n/a
Meas. Tech.
In Vitro Activity Assay
pH
7.5000±0.0000
Kd
20±2 nM
Citation
 Ranjitkar, P; Brock, AM; Maly, DJ Affinity reagents that target a specific inactive form of protein kinases. Chem Biol 17:195-206 (2010) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase Lck
Synonyms:
Protein YT16 | Proto-oncogene Lck | T cell-specific protein-tyrosine kinase | 2.7.10.2 | LSK | Lymphocyte cell-specific protein-tyrosine kinase | P56-LCK | Proto-oncogene tyrosine-protein kinase LCK | Leukocyte C-terminal Src kinase | LCK_HUMAN | LCK | Src/Lck kinase | Lymphocyte-specific protein tyrosine kinase
Type:
n/a
Mol. Mass.:
57987.83
Organism:
Human
Description:
P06239
Residue:
509
Sequence:
MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
  
Inhibitor
Name:
BDBM81374
Synonyms:
BODIPY-labeled probe, 4a
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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