Reaction Details Report a problem with these data
Target
Glutamate metabotropic receptor 5
Ligand
BDBM50060133
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2019
Citation
 Joly, C; Gomeza, J; Brabet, I; Curry, K; Bockaert, J; Pin, JP Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J Neurosci 15:3970-81 (1995) [PubMed] 
Target
Name:
Glutamate metabotropic receptor 5
Synonyms:
metabotropic glutamate 5b | metabotropic glutamate 5a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
120646.45
Organism:
Guinea pig
Description:
metabotropic glutamate 5a 0 PORCINE::H0VDS0
Residue:
1094
Sequence:
MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISAEEEEGLVRCVDGSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQHRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMRKDYFDYINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSVHINKKENLNQTAVIKPFPKSTESRGLGAGAGRRGGATGPTGGAGAASCAGAGPGGPEPPDAGAKALYDVAEGEEPFAAASVRPRSPSPISTLSQRAGSGGRTDDDVPSLHSEPAARSSSSQGSLMEQISSVVTSLSRANISELQLMMLSTGAPGPRGGRP
  
Inhibitor
Name:
BDBM50060133
Synonyms:
CHEMBL107845 | 1S, 3S-ACPD | 1-Amino-cyclopentane-1,3-dicarboxylic acid(cis-(1R,3R)-ACPD) | (1R,3R)-1-Amino-cyclopentane-1,3-dicarboxylic acid
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
N[C@@]1(CC[C@H](C1)C(O)=O)C(O)=O
Structure:
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