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Target
Alpha-2C adrenergic receptor
Ligand
BDBM81773
Substrate
n/a
Ki
6.91±n/a nM
Comments
PDSP_340
Citation
 O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB Characterization of [3H]RX821002 binding to alpha-2 adrenergic receptor subtypes. J Pharmacol Exp Ther 268:1362-7 (1994) [PubMed] 
Target
Name:
Alpha-2C adrenergic receptor
Synonyms:
adrenergic Alpha2C | Alpha-2C adrenergic receptor | ADA2C_RAT | Adra2c | Adrenergic receptor alpha | adrenergic Alpha2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49890.50
Organism:
Rat
Description:
adrenergic Alpha2 0 RAT::P22086
Residue:
458
Sequence:
MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
  
Inhibitor
Name:
BDBM81773
Synonyms:
BAM-1303 | CAS_115219-10-8 | BAM 1303
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13 |r|
Structure:
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