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Target
Cyclin-dependent kinase 1
Ligand
BDBM84533
Substrate
n/a
Meas. Tech.
Kinase Assay
pH
7.5000±0.0000
Temperature
303.1500±0.0000 K
IC50
0.23±0.0 nM
Citation
 Kunick, C; Zeng, Z; Gussio, R; Zaharevitz, D; Leost, M; Totzke, F; Schächtele, C; Kubbutat, MH; Meijer, L; Lemcke, T Structure-aided optimization of kinase inhibitors derived from alsterpaullone. Chembiochem 6:541-9 (2005) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | p34 protein kinase | CDK1_HUMAN | CDK1 | CDC2 | CDC28A | CDKN1 | P34CDC2
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Human
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM84533
Synonyms:
BDBM50375663 | Alsterpaullone derivative, 7
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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