Reaction Details Report a problem with these data
Target
Kit ligand
Ligand
BDBM84553
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.0000±0.0000
Temperature
295.1500±0.0000 K
IC50
>1.0e+4±n/a nM
Citation
 Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors. Chembiochem 6:531-40 (2005) [PubMed]  Article 
Target
Name:
Kit ligand
Synonyms:
c-Kit ligand | Mast cell growth factor | c-Kit | SCF_HUMAN | KITLG | MGF | SCF
Type:
Protein
Mol. Mass.:
30897.20
Organism:
Human
Description:
P21583
Residue:
273
Sequence:
MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPGMDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSSKDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKDSRVSVTKPFMLPPVAASSLRNDSSSSNRKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKRQPSLTRAVENIQINEEDNEISMLQEKEREFQEV
  
Inhibitor
Name:
BDBM84553
Synonyms:
Indirubin derivative, 28b | Indirubin derivative, 28a
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: