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Target
Alpha-galactosidase
Ligand
BDBM50260443
Substrate
n/a
Meas. Tech.
ChEBML_1693828
IC50
79±n/a nM
Citation
 Gavale, KS; Chavan, SR; Kumbhar, N; Kawade, S; Doshi, P; Khan, A; Dhavale, DD α-Geminal disubstituted pyrrolidine iminosugars and their C-4-fluoro analogues: Synthesis, glycosidase inhibition and molecular docking studies. Bioorg Med Chem 25:5148-5159 (2017) [PubMed]  Article 
Target
Name:
Alpha-galactosidase
Synonyms:
AGAL_COFAR | α-galactosidase | Alpha-galactosidase
Type:
Protein
Mol. Mass.:
41306.82
Organism:
Arabian coffee
Description:
n/a
Residue:
378
Sequence:
MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGYKYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTMPGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWGEEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGMTTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYGDLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQISAAVDAHDSKMYVLTPQ
  
Inhibitor
Name:
BDBM50260443
Synonyms:
CHEMBL4096086
Type:
Small organic molecule
Emp. Form.:
C6H11NO5
Mol. Mass.:
177.16
SMILES:
OC[C@@]1(NC[C@@H](O)[C@H]1O)C(O)=O |r|
Structure:
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