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Target
Pancreatic alpha-amylase
Ligand
BDBM50185127
Substrate
n/a
Meas. Tech.
ChEBML_1696961
IC50
>200000±n/a nM
Citation
 Zhang, BW; Xing, Y; Wen, C; Yu, XX; Sun, WL; Xiu, ZL; Dong, YS Pentacyclic triterpenes asα-glucosidase andα-amylase inhibitors: Structure-activity relationships and the synergism with acarbose. Bioorg Med Chem Lett 27:5065-5070 (2017) [PubMed]  Article 
Target
Name:
Pancreatic alpha-amylase
Synonyms:
1,4-alpha-D-glucan glucanohydrolase | PA | AMYP_PIG | AMY2
Type:
Protein
Mol. Mass.:
57088.07
Organism:
Pig
Description:
P00690
Residue:
511
Sequence:
MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSGAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL
  
Inhibitor
Name:
BDBM50185127
Synonyms:
30-hydroxy-11,30-dioxoolean-12-en-3beta-yl (2-O-beta-D-glucopyranosyluronic acid)-alpha-D-glucopyranosiduronic acid | glycyrrhizinic acid | (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid | glycyrrhizic acid | glyzyrrhizin | CHEMBL441687
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: