Reaction Details Report a problem with these data
Target
Growth hormone secretagogue receptor type 1
Ligand
BDBM50280856
Substrate
n/a
Meas. Tech.
ChEMBL_1722251 (CHEMBL4137251)
EC50
0.100000±n/a nM
Citation
 Gardelli, C; Wada, H; Ray, A; Caffrey, M; Llinas, A; Shamovsky, I; Tholander, J; Larsson, J; Sivars, U; Hultin, L; Andersson, U; Sanganee, HJ; Stenvall, K; Leidvik, B; Gedda, K; Jinton, L; Rydén Landergren, M; Karabelas, K Identification and Pharmacological Profile of an Indane Based Series of Ghrelin Receptor Full Agonists. J Med Chem 61:5974-5987 (2018) [PubMed]  Article 
Target
Name:
Growth hormone secretagogue receptor type 1
Synonyms:
Ghrelin receptor 1a (GHS-R1a) | GH-releasing peptide receptor | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | GHS-R | GHRP | GHSR_HUMAN | GHSR | Ghrelin receptor
Type:
Receptor
Mol. Mass.:
41334.57
Organism:
Human
Description:
Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a.
Residue:
366
Sequence:
MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
  
Inhibitor
Name:
BDBM50280856
Synonyms:
CHEMBL4172656
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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