Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50361373
Substrate
n/a
Meas. Tech.
ChEMBL_1727013 (CHEMBL4142291)
Ki
1900±n/a nM
Citation
 Hasan, M; Genovese, S; Fiorito, S; Epifano, F; Witt-Enderby, PA Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. J Nat Prod 80:3324-3329 (2017) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A protein | Mel-1A-R | Melatonin receptor type 1A | Mel1a melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin 1A | MTR1A_HUMAN | MTNR1A | Melatonin receptor
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Human
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50361373
Synonyms:
AURAPTENE
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: