Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50015749
Substrate
n/a
Meas. Tech.
ChEBML_29325
Ki
240±n/a nM
Citation
 Trivedi, BK; Bruns, RF [1,2,4]Triazolo[4,3-a]quinoxalin-4-amines: a new class of A1 receptor selective adenosine antagonists. J Med Chem 31:1011-4 (1988) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptors A1 | AA1R_RAT | Adora1 | Adenosine receptor
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rat
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50015749
Synonyms:
CHEMBL6958 | (1-Ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-isopropyl-amine
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCc1nnc2c(NC(C)C)nc3ccccc3n12
Structure:
Search PDB for entries with ligand similarity: