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Target
Prostaglandin G/H synthase 2
Ligand
BDBM54705
Substrate
n/a
Meas. Tech.
ChEMBL_1776567 (CHEMBL4233559)
IC50
26300±n/a nM
Citation
 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Synthesis and biological properties of aryl methyl sulfones. Bioorg Med Chem 26:4113-4126 (2018) [PubMed]  Article 
Target
Name:
Prostaglandin G/H synthase 2
Synonyms:
Cyclooxygenase-1 (COX-1) | Cyclooxygenase-2 (COX-2) | PGH2_SHEEP | PTGS2 | COX2 | Prostaglandin G/H synthase (cyclooxygenase) | Prostaglandin G/H synthase (Cyclooxygenase-2)
Type:
Protein
Mol. Mass.:
68976.98
Organism:
Sheep
Description:
n/a
Residue:
603
Sequence:
MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL
  
Inhibitor
Name:
BDBM54705
Synonyms:
calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate | cid_16219353 | CHEMBL1297 | UNM-0000306101 | Fenoprofen | calcium;2-(3-phenoxyphenyl)propionic acid;hydrate
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: