Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50386790
Substrate
n/a
Meas. Tech.
ChEMBL_1778690 (CHEMBL4235682)
EC50
5100±n/a nM
Citation
 Sun, Z; Zhou, T; Pan, X; Yang, Y; Huan, Y; Xiao, Z; Shen, Z; Liu, Z Design, synthesis and biological evaluation of a series of novel GPR40 agonists containing nitrogen heterocyclic rings. Bioorg Med Chem Lett 28:3050-3056 (2018) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
G-protein Coupled Receptor 40 | FFAR1_HUMAN | FFAR1 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Human
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50386790
Synonyms:
CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US11905230, Example TAK-875
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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