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Target
Retinal dehydrogenase 2
Ligand
BDBM50466622
Substrate
n/a
Meas. Tech.
ChEMBL_1793482 (CHEMBL4265401)
Ki
128±n/a nM
Citation
 Harper, AR; Le, AT; Mather, T; Burgett, A; Berry, W; Summers, JA Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem 26:5766-5779 (2018) [PubMed]  Article 
Target
Name:
Retinal dehydrogenase 2
Synonyms:
1.2.1.36 | Aldehyde dehydrogenase family 1 member A2 | RALDH 2 | RALDH(II) | Retinal dehydrogenase 2 | Retinaldehyde-specific dehydrogenase type 2 | AL1A2_CHICK | ALDH1A2 | RALDH2
Type:
PROTEIN
Mol. Mass.:
56729.31
Organism:
Chicken
Description:
ChEMBL_117928
Residue:
518
Sequence:
MTSSKIEMPGEVKADPAALMASLHLLPSPTLNLEIKHTKIFINNEWQNSESGRVFPVYNPATGEQICEIQEADKVDTDKAVRAARLAFSLGSVWRRMDASERGQLLDKLADLVERDRAVLATMESLNSGKPFLQAFYVDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGFGPIVGAAIASHVGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIYVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGITEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTVDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGESGLREYSEVKTVTIKIPQKNS
  
Inhibitor
Name:
BDBM50466622
Synonyms:
CHEMBL4286209
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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