Reaction Details Report a problem with these data
Target
Cathepsin B-like protease
Ligand
BDBM50468725
Substrate
n/a
Meas. Tech.
ChEMBL_1801041 (CHEMBL4273333)
Ki
18200±n/a nM
Citation
 Fey, P; Chartomatsidou, R; Kiefer, W; Mottram, JC; Kersten, C; Schirmeister, T New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8. Eur J Med Chem 156:587-597 (2018) [PubMed]  Article 
Target
Name:
Cathepsin B-like protease
Synonyms:
Cathepsin B-like protease
Type:
PROTEIN
Mol. Mass.:
37241.03
Organism:
Leishmania major
Description:
ChEMBL_117828
Residue:
340
Sequence:
MALRAKSALCLVAVFALLLATTVSGLYAKPSDFPLLGKSFVAEVNSKAKGQWTASANNGYLVTGKSLGEVRKLMGVTDMSTEAVPPRNFSVEELQQDLPEFFDAAEHWPMCLTISEIRDQSNCGSCWAIAAVEAISDRYCTFGGVPDRRMSTSNLLSCCFICGLGCHGGIPTVAWLWWVWVGIATEDCQPYPFDPCSHHGNSEKYPPCPSTIYDTPKCNTTCERNEMDLVKYKGSTSYSVKGEKELMIELMTNGPLELTMQVYSDFVGYKSGVYKHVLGDFLGGHAVKLVGWGTQDGVPYWKVANSWNTDWGDKGYFLIQRGNNECKIESGGVAGIPAQE
  
Inhibitor
Name:
BDBM50468725
Synonyms:
CHEMBL4279254
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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