Reaction Details Report a problem with these data
Target
Retinoic acid receptor gamma
Ligand
BDBM50471290
Substrate
n/a
Meas. Tech.
ChEMBL_196004 (CHEMBL797868)
Kd
7258±n/a nM
Citation
 Teng, M; Duong, TT; Johnson, AT; Klein, ES; Wang, L; Khalifa, B; Chandraratna, RA Identification of highly potent retinoic acid receptor alpha-selective antagonists. J Med Chem 40:2445-51 (1997) [PubMed]  Article 
Target
Name:
Retinoic acid receptor gamma
Synonyms:
NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50345.43
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458016
Residue:
454
Sequence:
MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
  
Inhibitor
Name:
BDBM50471290
Synonyms:
CHEMBL81978
Type:
Small organic molecule
Emp. Form.:
C26H21BrFNO4
Mol. Mass.:
510.352
SMILES:
Cc1ccc(cc1)C1=CC(C)(C)Oc2c(Br)cc(cc12)C(=O)Nc1ccc(C(O)=O)c(F)c1 |t:8|
Structure:
Search PDB for entries with ligand similarity: