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Target
Retinoic acid receptor beta
Ligand
BDBM50471288
Substrate
n/a
Meas. Tech.
ChEMBL_195490 (CHEMBL798912)
Kd
898±n/a nM
Citation
 Teng, M; Duong, TT; Johnson, AT; Klein, ES; Wang, L; Khalifa, B; Chandraratna, RA Identification of highly potent retinoic acid receptor alpha-selective antagonists. J Med Chem 40:2445-51 (1997) [PubMed]  Article 
Target
Name:
Retinoic acid receptor beta
Synonyms:
HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50498.70
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458015
Residue:
455
Sequence:
MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
  
Inhibitor
Name:
BDBM50471288
Synonyms:
CHEMBL312198
Type:
Small organic molecule
Emp. Form.:
C26H20BrF2NO4
Mol. Mass.:
528.342
SMILES:
Cc1ccc(cc1)C1=CC(C)(C)Oc2c(Br)cc(cc12)C(=O)Nc1cc(F)c(C(O)=O)c(F)c1 |t:8|
Structure:
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