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Target
Alpha-2A adrenergic receptor
Ligand
BDBM50473224
Substrate
n/a
Meas. Tech.
ChEMBL_33794 (CHEMBL648119)
EC50
11±n/a nM
Citation
 Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C 2-amino-2-oxazolines as subtype selective alpha(2) adrenoceptor agonists. J Med Chem 43:1699-704 (2000) [PubMed]  Article 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
ADRA2R | Adrenergic receptor alpha | ADRA2A | Adrenergic alpha2A | Alpha-2 adrenergic receptor subtype C10 | alpha-2A adrenergic receptor [Homo sapiens] | ADRAR | ADA2A_HUMAN | Alpha-2AAR | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor
Type:
Enzyme
Mol. Mass.:
48979.91
Organism:
Human
Description:
P08913
Residue:
465
Sequence:
MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM50473224
Synonyms:
CHEMBL296660
Type:
Small organic molecule
Emp. Form.:
C13H22N2O
Mol. Mass.:
222.33
SMILES:
CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5|
Structure:
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