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Target
Cholesteryl ester transfer protein
Ligand
BDBM50473322
Substrate
n/a
Meas. Tech.
ChEMBL_48921 (CHEMBL660751)
Kd
32000±n/a nM
Citation
 Baumann, M; Bischoff, H; Schmidt, D; Griesinger, C Combinatorial synthesis of cholesterol ester transfer protein-mRNA ligands and screening by nondenaturating gel-electrophoresis. J Med Chem 44:2172-7 (2001) [PubMed]  Article 
Target
Name:
Cholesteryl ester transfer protein
Synonyms:
Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I | CETP_HUMAN | CETP
Type:
Enzyme
Mol. Mass.:
54751.53
Organism:
Human
Description:
P11597
Residue:
493
Sequence:
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
  
Inhibitor
Name:
BDBM50473322
Synonyms:
CHEMBL302452
Type:
Small organic molecule
Emp. Form.:
C45H73N11O9S
Mol. Mass.:
944.21
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(N)=O
Structure:
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